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Induction of somatic mutations by low-dose X-rays: the challenge in recognizing radiation-induced events

It is difficult to distinguish radiation-induced events from spontaneous events during induction of stochastic effects, especially in the case of low-dose or low-dose-rate exposures. By using a hypersensitive system for detecting somatic mutations at the HPRT1 locus, we investigated the frequency an...

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Detalles Bibliográficos
Autores principales: Nagashima, Haruki, Shiraishi, Kumiko, Ohkawa, Saori, Sakamoto, Yuki, Komatsu, Kenshi, Matsuura, Shinya, Tachibana, Akira, Tauchi, Hiroshi
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Oxford University Press 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5941164/
https://www.ncbi.nlm.nih.gov/pubmed/29053826
http://dx.doi.org/10.1093/jrr/rrx053