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Clinical-grade generation of peptide-stimulated CMV/EBV-specific T cells from G-CSF mobilized stem cell grafts

BACKGROUND: A major complication after allogeneic hematopoietic stem cell transplantation (aSCT) is the reactivation of herpesviruses such as cytomegalovirus (CMV) and Epstein–Barr virus (EBV). Both viruses cause significant mortality and compromise quality of life after aSCT. Preventive transfer of...

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Detalles Bibliográficos
Autores principales: Gary, Regina, Aigner, Michael, Moi, Stephanie, Schaffer, Stefanie, Gottmann, Anja, Maas, Stefanie, Zimmermann, Robert, Zingsem, Jürgen, Strobel, Julian, Mackensen, Andreas, Mautner, Josef, Moosmann, Andreas, Gerbitz, Armin
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5941463/
https://www.ncbi.nlm.nih.gov/pubmed/29743075
http://dx.doi.org/10.1186/s12967-018-1498-3