Cargando…

Clinical-grade generation of peptide-stimulated CMV/EBV-specific T cells from G-CSF mobilized stem cell grafts

BACKGROUND: A major complication after allogeneic hematopoietic stem cell transplantation (aSCT) is the reactivation of herpesviruses such as cytomegalovirus (CMV) and Epstein–Barr virus (EBV). Both viruses cause significant mortality and compromise quality of life after aSCT. Preventive transfer of...

Descripción completa

Detalles Bibliográficos
Autores principales:	Gary, Regina, Aigner, Michael, Moi, Stephanie, Schaffer, Stefanie, Gottmann, Anja, Maas, Stefanie, Zimmermann, Robert, Zingsem, Jürgen, Strobel, Julian, Mackensen, Andreas, Mautner, Josef, Moosmann, Andreas, Gerbitz, Armin
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	BioMed Central 2018
Materias:	Methodology
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5941463/ https://www.ncbi.nlm.nih.gov/pubmed/29743075 http://dx.doi.org/10.1186/s12967-018-1498-3

Ejemplares similares

Prevention of CMV/EBV reactivation by double-specific T cells in patients after allogeneic stem cell transplantation: results from the randomized phase I/IIa MULTIVIR-01 study
por: Gerbitz, Armin, et al.
Publicado: (2023)

Reconstitution of EBV-directed T cell immunity by adoptive transfer of peptide-stimulated T cells in a patient after allogeneic stem cell transplantation for AITL
por: Lammoglia Cobo, María Fernanda, et al.
Publicado: (2022)

A Diverse Repertoire of CD4 T Cells Targets the Immediate-Early 1 Protein of Human Cytomegalovirus
por: Ameres, Stefanie, et al.
Publicado: (2015)

Depletion of donor-specific anti-HLA A2 alloantibodies in a hematopoietic cell transplant recipient using directed mismatched platelet transfusions
por: Spriewald, Bernd M., et al.
Publicado: (2018)

S291: LONG-TERM SAFETY AND EFFICACY OF CMV/EBV-SPECIFIC T CELLS FOR CMV AND EBV CO-REACTIVATION AFTER HAPLOIDENTICAL STEM CELL TRANSPLANTATION
por: Xuying, Pei, et al.
Publicado: (2023)

Presentation of an Immunodominant Immediate-Early CD8+ T Cell Epitope Resists Human Cytomegalovirus Immunoevasion
por: Ameres, Stefanie, et al.
Publicado: (2013)

GMP-production of purified human B lymphocytes for the adoptive transfer in patients after allogeneic hematopoietic stem cell transplantation
por: Tittlbach, Hannes, et al.
Publicado: (2017)

Progress in EBV Vaccines
por: van Zyl, Dwain G., et al.
Publicado: (2019)

Virus and Autoantigen-Specific CD4+ T Cells Are Key Effectors in a SCID Mouse Model of EBV-Associated Post-Transplant Lymphoproliferative Disorders
por: Linnerbauer, Stefanie, et al.
Publicado: (2014)

The prevalence of EBV and CMV DNA in epithelial ovarian cancer
por: Ingerslev, Kasper, et al.
Publicado: (2019)

Latent Membrane Protein LMP2A Impairs Recognition of EBV-Infected Cells by CD8+ T Cells
por: Rancan, Chiara, et al.
Publicado: (2015)

Age and CMV-Infection Jointly Affect the EBV-Specific CD8(+) T-Cell Repertoire
por: Lanfermeijer, Josien, et al.
Publicado: (2021)

Targeting c-MYC with T-Cells
por: Helm, Florian, et al.
Publicado: (2013)

CMV and EBV Co-Infection in HIV-Infected Children: Infection Rates and Analysis of Differential Expression of Cytokines in HIV Mono- and HIV–CMV–EBV Co-Infected Groups
por: Nazim, Fizza, et al.
Publicado: (2022)

Control of Epstein-Barr virus infection in vitro by T helper cells specific for virion glycoproteins
por: Adhikary, Dinesh, et al.
Publicado: (2006)

Congenital and Postnatal CMV and EBV Acquisition in HIV-Infected Zimbabwean Infants
por: Gumbo, Hlanai, et al.
Publicado: (2014)

IgM Positivity for Both EBV and CMV: A Clinical Conundrum
por: Jhaveri, Tulip A, et al.
Publicado: (2022)

The EBV Immunoevasins vIL-10 and BNLF2a Protect Newly Infected B Cells from Immune Recognition and Elimination
por: Jochum, Simon, et al.
Publicado: (2012)

Functional Differences Between EBV- and CMV-Specific CD8(+) T cells Demonstrate Heterogeneity of T cell Dysfunction in CLL
por: Hofland, Tom, et al.
Publicado: (2020)

Third-party CMV- and EBV-specific T-cells for first viral reactivation after allogeneic stem cell transplant
por: Jiang, Wei, et al.
Publicado: (2022)

Immune recovery and the risk of CMV/ EBV reactivation in children post allogeneic haematopoietic stem cell transplantation
por: Janeczko, Małgorzata, et al.
Publicado: (2016)

Coinfection with EBV/CMV and other respiratory agents in children with suspected infectious mononucleosis
por: Wang, Xia, et al.
Publicado: (2010)

The prevalence of CMV and EBV among the patients with the colorectal cancer; a molecular approach
por: Arastefar, Amir, et al.
Publicado: (2015)

Overall avidity declines in TCR repertoires during latent CMV but not EBV infection
por: Couturaud, Barbara, et al.
Publicado: (2023)

Seroprevalence of HHV-8, CMV, and EBV among the general population in Ghana, West Africa
por: Adjei, Andrew A, et al.
Publicado: (2008)

Antibodies to early EBV, CMV, and HHV6 antigens in systemic lupus erythematosus patients
por: Rasmussen, NS, et al.
Publicado: (2015)

Hemophagocytic Lymphohistiocytosis in a Patient With Hodgkin lymphoma and Concurrent EBV, CMV, and Candida Infections
por: Mustafa Ali, Moaath, et al.
Publicado: (2017)

Association of CMV-Specific T Cell-Mediated Immunity with CMV DNAemia and Development of CMV Disease in HIV-1–Infected Individuals
por: Aichelburg, Maximilian C., et al.
Publicado: (2015)

M‐CSF directs myeloid and NK cell differentiation to protect from CMV after hematopoietic cell transplantation
por: Kandalla, Prashanth K, et al.
Publicado: (2023)

Effects of tofacitinib on lymphocyte sub-populations, CMV and EBV viral load in patients with plaque psoriasis
por: Valenzuela, Fernando, et al.
Publicado: (2015)

CMV and EBV targets recognized by tumor-infiltrating B lymphocytes in pancreatic cancer and brain tumors
por: Meng, Qingda, et al.
Publicado: (2018)

Lower CMV and EBV Exposure in Children With Kawasaki Disease Suggests an Under-Challenged Immune System
por: van Stijn, Diana, et al.
Publicado: (2021)

Lymphocyte Immune Response and T Cell Differentiation in Fontan Patients with protein-losing enteropathy
por: Moosmann, Julia, et al.
Publicado: (2021)

Immunodominance of Lytic Cycle Antigens in Epstein-Barr Virus-Specific CD4+ T Cell Preparations for Therapy
por: Adhikary, Dinesh, et al.
Publicado: (2007)

Role of CAR T Cell Metabolism for Therapeutic Efficacy
por: Rial Saborido, Judit, et al.
Publicado: (2022)

CD56-negative NK cells with impaired effector function expand in CMV and EBV co-infected healthy donors with age
por: Müller-Durovic, Bojana, et al.
Publicado: (2019)

Toward a Rapid Production of Multivirus-Specific T Cells Targeting BKV, Adenovirus, CMV, and EBV from Umbilical Cord Blood
por: Dave, Hema, et al.
Publicado: (2017)

Prevalence and molecular epidemiology of CMV and EBV among nurses working in pediatrics, transplantology, and primary health care
por: Zając, Patrycja W., et al.
Publicado: (2020)

Corrigendum: Lower CMV and EBV Exposure in Children With Kawasaki Disease Suggests an Under-Challenged Immune System
por: van Stijn, Diana, et al.
Publicado: (2021)

Adoptive transfer of rapidly-generated multivirus-specific T cells to treat Adv, EBV, CMV, BK and HHV6 infections of HSCT recipients
por: Papadopoulou, Anastasia, et al.
Publicado: (2013)

Cannot write session to /tmp/vufind_sessions/sess_enc9sn5u4drnlvr2kgds4cb7gl