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Limited utility of tissue micro-arrays in detecting intra-tumoral heterogeneity in stem cell characteristics and tumor progression markers in breast cancer

BACKGROUND: Intra-tumoral heterogeneity has been recently addressed in different types of cancer, including breast cancer. A concept describing the origin of intra-tumoral heterogeneity is the cancer stem-cell hypothesis, proposing the existence of cancer stem cells that can self-renew limitlessly a...

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Detalles Bibliográficos
Autores principales: Kündig, Pascale, Giesen, Charlotte, Jackson, Hartland, Bodenmiller, Bernd, Papassotirolopus, Bärbel, Freiberger, Sandra Nicole, Aquino, Catharine, Opitz, Lennart, Varga, Zsuzsanna
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5941467/
https://www.ncbi.nlm.nih.gov/pubmed/29739401
http://dx.doi.org/10.1186/s12967-018-1495-6