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Global DNA methylation changes spanning puberty are near predicted estrogen-responsive genes and enriched for genes involved in endocrine and immune processes

BACKGROUND: The changes that occur during puberty have been implicated in susceptibility to a wide range of diseases later in life, many of which are characterized by sex-specific differences in prevalence. Both genetic and environmental factors have been associated with the onset or delay of pubert...

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Detalles Bibliográficos
Autores principales: Thompson, Emma E., Nicodemus-Johnson, Jessie, Kim, Kyung Won, Gern, James E., Jackson, Daniel J., Lemanske, Robert F., Ober, Carole
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5941468/
https://www.ncbi.nlm.nih.gov/pubmed/29760811
http://dx.doi.org/10.1186/s13148-018-0491-2