Cargando…

MicroRNA-495 inhibits the high glucose-induced inflammation, differentiation and extracellular matrix accumulation of cardiac fibroblasts through downregulation of NOD1

BACKGROUND: MicroRNAs (miRNAs) have physiological and pathophysiological functions that are involved in the regulation of cardiac fibrosis. This study aimed to investigate the effects of miR-495 on high glucose-induced cardiac fibrosis in human cardiac fibroblasts (CFs) and to establish the mechanis...

Descripción completa

Detalles Bibliográficos
Autores principales: Wang, Xiaowei, Jin, Haiying, Jiang, Shifeng, Xu, Yanlan
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5941488/
https://www.ncbi.nlm.nih.gov/pubmed/29760746
http://dx.doi.org/10.1186/s11658-018-0089-x