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Induction of the acid inducible lipF promoter is reversibly inhibited in pH ranges of pH 4.2-4.0

OBJECTIVE: In the human body pathogenic mycobacteria encounter low pH within the phagosomes of macrophages where they reside after being internalized by the host cell. Low pH within macrophages has been shown to induce expression of a variety of genes within these bacteria. It had been previously ob...

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Detalles Bibliográficos
Autores principales: Torres, Rachelle, Dorriz, Donna, Saviola, Beatrice
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5941605/
https://www.ncbi.nlm.nih.gov/pubmed/29739437
http://dx.doi.org/10.1186/s13104-018-3370-1