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Induction of the acid inducible lipF promoter is reversibly inhibited in pH ranges of pH 4.2-4.0
OBJECTIVE: In the human body pathogenic mycobacteria encounter low pH within the phagosomes of macrophages where they reside after being internalized by the host cell. Low pH within macrophages has been shown to induce expression of a variety of genes within these bacteria. It had been previously ob...
Autores principales: | Torres, Rachelle, Dorriz, Donna, Saviola, Beatrice |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
BioMed Central
2018
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5941605/ https://www.ncbi.nlm.nih.gov/pubmed/29739437 http://dx.doi.org/10.1186/s13104-018-3370-1 |
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