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Naked mole-rat cortical neurons are resistant to acid-induced cell death

Regulation of brain pH is a critical homeostatic process and changes in brain pH modulate various ion channels and receptors and thus neuronal excitability. Tissue acidosis, resulting from hypoxia or hypercapnia, can activate various proteins and ion channels, among which acid-sensing ion channels (...

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Detalles Bibliográficos
Autores principales: Husson, Zoé, Smith, Ewan St. John
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5941639/
https://www.ncbi.nlm.nih.gov/pubmed/29739425
http://dx.doi.org/10.1186/s13041-018-0369-4