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Integrative analyses of genes and microRNA expressions in human trisomy 21 placentas

BACKGROUND: The most frequent chromosomal aneuploidy is trisomy 21 (T21) that is caused by an extra copy of chromosome 21. The imbalance of whole genome including genes and microRNAs contributes to the various phenotypes of T21. However, the integrative association between genes and microRNAs in the...

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Detalles Bibliográficos
Autores principales: Lim, Ji Hyae, Han, You Jung, Kim, Hyun Jin, Kim, Moon Young, Park, So Yeon, Cho, Youl-Hee, Ryu, Hyun Mee
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5941645/
https://www.ncbi.nlm.nih.gov/pubmed/29739397
http://dx.doi.org/10.1186/s12920-018-0361-y