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Evaluating Hepatobiliary Transport with (18)F-Labeled Bile Acids: The Effect of Radiolabel Position and Bile Acid Structure on Radiosynthesis and In Vitro and In Vivo Performance

INTRODUCTION: An in vivo determination of bile acid hepatobiliary transport efficiency can be of use in liver disease and preclinical drug development. Given the increased interest in bile acid Positron Emission Tomography- (PET-) imaging, a further understanding of the impact of 18-fluorine substit...

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Detalles Bibliográficos
Autores principales:	De Lombaerde, Stef, Kersemans, Ken, Neyt, Sara, Verhoeven, Jeroen, Vanhove, Christian, De Vos, Filip
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Hindawi 2018
Materias:	Research Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5941726/ https://www.ncbi.nlm.nih.gov/pubmed/29853807 http://dx.doi.org/10.1155/2018/6345412

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