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Abnormal PITX1 gene methylation in adolescent idiopathic scoliosis: a pilot study
BACKGROUND: The gene of pituitary homeobox 1 (PITX1) has been reported to be down-regulated in adolescent idiopathic scoliosis (AIS), of which the cause has not been well addressed. The abnormal DNA methylation was recently assumed to be an important mechanism for the down-regulated genes expression...
Autores principales: | , , , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
BioMed Central
2018
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5941792/ https://www.ncbi.nlm.nih.gov/pubmed/29743058 http://dx.doi.org/10.1186/s12891-018-2054-2 |