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Overexpression of Thioredoxin-1 Blocks Morphine-Induced Conditioned Place Preference Through Regulating the Interaction of γ-Aminobutyric Acid and Dopamine Systems

Morphine is one kind of opioid, which is currently the most effective widely utilized pain relieving pharmaceutical. Long-term administration of morphine leads to dependence and addiction. Thioredoxin-1 (Trx-1) is an important redox regulating protein and works as a neurotrophic cofactor. Our previo...

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Detalles Bibliográficos
Autores principales: Li, Xiang, Huang, Mengbing, Yang, Lihua, Guo, Ningning, Yang, Xiaoyan, Zhang, Zhimin, Bai, Ming, Ge, Lu, Zhou, Xiaoshuang, Li, Ye, Bai, Jie
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5941988/
https://www.ncbi.nlm.nih.gov/pubmed/29770121
http://dx.doi.org/10.3389/fneur.2018.00309