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Reexploring 5-methoxyindole-2-carboxylic acid (MICA) as a potential antidiabetic agent

5-Methoxyindole-2-carboxylic acid (MICA) is a potent hypoglycemic agent that inhibits gluconeogenesis in the liver. It is also a well-known inhibitor of mitochondrial dihydrolipoamide dehydrogenase. MICA was extensively studied in the 1960s and 1970s and was once tested for its antidiabetic effect i...

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Detalles Bibliográficos
Autor principal: Yan, Liang-Jun
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Dove Medical Press 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5942165/
https://www.ncbi.nlm.nih.gov/pubmed/29765243
http://dx.doi.org/10.2147/DMSO.S166485