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Deposition and transport of linezolid mediated by a synthetic surfactant Synsurf(®) within a pressurized metered dose inhaler: a Calu-3 model

BACKGROUND: Previous studies in our laboratory demonstrated that a synthetic peptide containing lung surfactant enhances the permeability of chemical compounds through bronchial epithelium. The purpose of this study was to test two formulations of Synsurf(®) combined with linezolid as respirable com...

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Detalles Bibliográficos
Autores principales: van Rensburg, Lyné, van Zyl, Johann M, Smith, Johan
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Dove Medical Press 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5942168/
https://www.ncbi.nlm.nih.gov/pubmed/29765201
http://dx.doi.org/10.2147/DDDT.S147035