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Deposition and transport of linezolid mediated by a synthetic surfactant Synsurf(®) within a pressurized metered dose inhaler: a Calu-3 model
BACKGROUND: Previous studies in our laboratory demonstrated that a synthetic peptide containing lung surfactant enhances the permeability of chemical compounds through bronchial epithelium. The purpose of this study was to test two formulations of Synsurf(®) combined with linezolid as respirable com...
Autores principales: | van Rensburg, Lyné, van Zyl, Johann M, Smith, Johan |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Dove Medical Press
2018
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5942168/ https://www.ncbi.nlm.nih.gov/pubmed/29765201 http://dx.doi.org/10.2147/DDDT.S147035 |
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