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MGMT assessment in pituitary adenomas: comparison of different immunohistochemistry fixation chemicals

PURPOSE: Despite the established role of O6-methyl-guanine-DNA methyltransferase (MGMT) as a marker for temozolomide response, consensus of the most reliable method to assess MGMT expression in pituitary adenomas is still missing. Currently, immunohistochemistry (IHC) assessment of formaldehyde fixe...

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Detalles Bibliográficos
Autores principales: Micko, Alexander S. G., Höftberger, Romana, Wöhrer, Adelheid, Millesi, Matthias, Knosp, Engelbert, Wolfsberger, Stefan
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Springer US 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5942339/
https://www.ncbi.nlm.nih.gov/pubmed/29344904
http://dx.doi.org/10.1007/s11102-018-0862-x