Structural basis for membrane anchoring and fusion regulation of the Herpes Simplex Virus fusogen gB

Viral fusogens merge viral and cell membranes during cell penetration. Their ectodomains drive fusion by undergoing large-scale refolding, but little is known about the functionally important regions located within or near the membrane. Here, we report the crystal structure of the full-length glycop...

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Detalles Bibliográficos
Autores principales: Cooper, Rebecca S., Georgieva, Elka R., Borbat, Peter P., Freed, Jack H., Heldwein, Ekaterina E.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: 2018
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5942590/
https://www.ncbi.nlm.nih.gov/pubmed/29728654
http://dx.doi.org/10.1038/s41594-018-0060-6

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5942590/
https://www.ncbi.nlm.nih.gov/pubmed/29728654
http://dx.doi.org/10.1038/s41594-018-0060-6

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