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Structural basis for membrane anchoring and fusion regulation of the Herpes Simplex Virus fusogen gB
Viral fusogens merge viral and cell membranes during cell penetration. Their ectodomains drive fusion by undergoing large-scale refolding, but little is known about the functionally important regions located within or near the membrane. Here, we report the crystal structure of the full-length glycop...
Autores principales: | Cooper, Rebecca S., Georgieva, Elka R., Borbat, Peter P., Freed, Jack H., Heldwein, Ekaterina E. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
2018
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5942590/ https://www.ncbi.nlm.nih.gov/pubmed/29728654 http://dx.doi.org/10.1038/s41594-018-0060-6 |
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