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Paquinimod prevents development of diabetes in the non-obese diabetic (NOD) mouse

Quinoline-3-carboxamides (Q compounds) are immunomodulatory compounds that have shown efficacy both in autoimmune disease and cancer. We have in here investigated the impact of one such compound, paquinimod, on the development of diabetes in the NOD mouse model for type I diabetes (T1D). In cohorts...

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Detalles Bibliográficos
Autores principales: Tahvili, Sahar, Törngren, Marie, Holmberg, Dan, Leanderson, Tomas, Ivars, Fredrik
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5942776/
https://www.ncbi.nlm.nih.gov/pubmed/29742113
http://dx.doi.org/10.1371/journal.pone.0196598