White matter hyperintensities and the mediating role of cerebral amyloid angiopathy in dominantly-inherited Alzheimer’s disease

INTRODUCTION: White matter hyperintensity (WMH) volume on MRI is increased among presymptomatic individuals with autosomal dominant mutations for Alzheimer’s disease (AD). One potential explanation is that WMH, conventionally considered a marker of cerebrovascular disease, are a reflection of cerebr...

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Detalles Bibliográficos
Autores principales: Lee, Seonjoo, Zimmerman, Molly E., Narkhede, Atul, Nasrabady, Sara E., Tosto, Giuseppe, Meier, Irene B., Benzinger, Tammie L. S., Marcus, Daniel S., Fagan, Anne M., Fox, Nick C., Cairns, Nigel J., Holtzman, David M., Buckles, Virginia, Ghetti, Bernardino, McDade, Eric, Martins, Ralph N., Saykin, Andrew J., Masters, Colin L., Ringman, John M., Fӧrster, Stefan, Schofield, Peter R., Sperling, Reisa A., Johnson, Keith A., Chhatwal, Jasmeer P., Salloway, Stephen, Correia, Stephen, Jack, Clifford R., Weiner, Michael, Bateman, Randall J., Morris, John C., Mayeux, Richard, Brickman, Adam M.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2018
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5942789/
https://www.ncbi.nlm.nih.gov/pubmed/29742105
http://dx.doi.org/10.1371/journal.pone.0195838

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5942789/
https://www.ncbi.nlm.nih.gov/pubmed/29742105
http://dx.doi.org/10.1371/journal.pone.0195838

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