RosettaAntibodyDesign (RAbD): A general framework for computational antibody design

A structural-bioinformatics-based computational methodology and framework have been developed for the design of antibodies to targets of interest. RosettaAntibodyDesign (RAbD) samples the diverse sequence, structure, and binding space of an antibody to an antigen in highly customizable protocols for...

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Detalles Bibliográficos
Autores principales: Adolf-Bryfogle, Jared, Kalyuzhniy, Oleks, Kubitz, Michael, Weitzner, Brian D., Hu, Xiaozhen, Adachi, Yumiko, Schief, William R., Dunbrack, Roland L.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2018
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5942852/
https://www.ncbi.nlm.nih.gov/pubmed/29702641
http://dx.doi.org/10.1371/journal.pcbi.1006112

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5942852/
https://www.ncbi.nlm.nih.gov/pubmed/29702641
http://dx.doi.org/10.1371/journal.pcbi.1006112

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