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Structures of monomeric and oligomeric forms of the Toxoplasma gondii perforin-like protein 1

Toxoplasma and Plasmodium are the parasitic agents of toxoplasmosis and malaria, respectively, and use perforin-like proteins (PLPs) to invade host organisms and complete their life cycles. The Toxoplasma gondii PLP1 (TgPLP1) is required for efficient exit from parasitophorous vacuoles in which prol...

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Detalles Bibliográficos
Autores principales: Ni, Tao, Williams, Sophie I., Rezelj, Saša, Anderluh, Gregor, Harlos, Karl, Stansfeld, Phillip J., Gilbert, Robert J. C.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Association for the Advancement of Science 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5943054/
https://www.ncbi.nlm.nih.gov/pubmed/29750191
http://dx.doi.org/10.1126/sciadv.aaq0762