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Gadolinium Retention, Brain T1 Hyperintensity, and Endogenous Metals: A Comparative Study of Macrocyclic Versus Linear Gadolinium Chelates in Renally Sensitized Rats

OBJECTIVES: This preclinical study was designed to compare gadolinium (Gd) brain uptake after repeated injections of a macrocyclic Gd-based contrast agent (GBCA) (gadoterate meglumine) or 2 linear GBCAs (L-GBCAs) (gadobenate dimeglumine or gadodiamide) on a translational model of moderate renal impa...

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Detalles Bibliográficos
Autores principales: Rasschaert, Marlène, Emerit, Andréa, Fretellier, Nathalie, Factor, Cécile, Robert, Philippe, Idée, Jean-Marc, Corot, Claire
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Lippincott Williams & Wilkins 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5943076/
https://www.ncbi.nlm.nih.gov/pubmed/29329151
http://dx.doi.org/10.1097/RLI.0000000000000447