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Effective assessment of low times MET amplification in pleural effusion after epidermal growth factor receptor-tyrosine kinase inhibitors (EGFR-TKIs) acquired resistance: Cases report

RATIONALE: The mechanism of the first-generation epidermal growth factor receptor-tyrosine kinase inhibitors (EGFR-TKIs) acquired resistance included T790M mutation, cellular-mesenchymal to epithelial transition factor (MET) or EGFR amplification, PIK3CA mutation, and transformation to small cell lu...

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Detalles Bibliográficos
Autores principales: Wang, Chang-guo, Zeng, Da-xiong, Huang, Jian-an, Jiang, Jun-hong
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Wolters Kluwer Health 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5943108/
https://www.ncbi.nlm.nih.gov/pubmed/29505507
http://dx.doi.org/10.1097/MD.0000000000009021