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Potential of quantitative SEPT9 and SHOX2 methylation in plasmatic circulating cell-free DNA as auxiliary staging parameter in colorectal cancer: a prospective observational cohort study

BACKGROUND: Septin 9 (SEPT9) and short stature homeobox 2 (SHOX2) methylation in circulating cell-free DNA (ccfDNA) are powerful biomarkers for colorectal cancer (CRC) screening, as well as head and neck squamous cell carcinoma staging and monitoring. In the present study, we investigated SEPT9 and...

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Detalles Bibliográficos
Autores principales: Bergheim, Julia, Semaan, Alexander, Gevensleben, Heidrun, Groening, Susanne, Knoblich, Andreas, Dietrich, Jörn, Weber, Julia, Kalff, Jörg C., Bootz, Friedrich, Kristiansen, Glen, Dietrich, Dimo
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5943265/
https://www.ncbi.nlm.nih.gov/pubmed/29610456
http://dx.doi.org/10.1038/s41416-018-0035-8