Classical and alternative complement activation on photoreceptor outer segments drives monocyte-dependent retinal atrophy

Geographic atrophy (GA), the advanced form of dry age-related macular degeneration (AMD), is characterized by progressive loss of retinal pigment epithelium cells and photoreceptors in the setting of characteristic extracellular deposits and remains a serious unmet medical need. While genetic predis...

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Detalles Bibliográficos
Autores principales: Katschke, Kenneth J., Xi, Hongkang, Cox, Christian, Truong, Tom, Malato, Yann, Lee, Wyne P., McKenzie, Brent, Arceo, Rommel, Tao, Jianhua, Rangell, Linda, Reichelt, Mike, Diehl, Lauri, Elstrott, Justin, Weimer, Robby M, van Lookeren Campagne, Menno
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2018
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5943270/
https://www.ncbi.nlm.nih.gov/pubmed/29743491
http://dx.doi.org/10.1038/s41598-018-25557-8

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5943270/
https://www.ncbi.nlm.nih.gov/pubmed/29743491
http://dx.doi.org/10.1038/s41598-018-25557-8

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