Inhibitor of apoptosis proteins are required for effective fusion of autophagosomes with lysosomes

Inhibitor of Apoptosis Proteins act as E3 ubiquitin ligases to regulate NF-κB signalling from multiple pattern recognition receptors including NOD2, as well as TNF Receptor Superfamily members. Loss of XIAP in humans causes X-linked Lymphoproliferative disease type 2 (XLP-2) and is often associated...

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Detalles Bibliográficos
Autores principales: Gradzka, Sylwia, Thomas, Oliver S., Kretz, Oliver, Haimovici, Aladin, Vasilikos, Lazaros., Wong, Wendy Wei-Lynn, Häcker, Georg, Gentle, Ian E.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2018
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5943300/
https://www.ncbi.nlm.nih.gov/pubmed/29743550
http://dx.doi.org/10.1038/s41419-018-0508-y

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5943300/
https://www.ncbi.nlm.nih.gov/pubmed/29743550
http://dx.doi.org/10.1038/s41419-018-0508-y

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