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The mechanism study of lentiviral vector carrying methioninase enhances the sensitivity of drug-resistant gastric cancer cells to Cisplatin

BACKGROUND: To investigate the mechanism of lentiviral vector carrying methioninase enhances the sensitivity of drug-resistant gastric cancer cells to Cisplatin. METHODS: Death receptors, anti-apoptotic protein, NF-κB, and TRAIL pathway-related factors were detected. The influence of LV-METase trans...

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Detalles Bibliográficos
Autores principales: Xin, Lin, Yang, Wei-Feng, Zhang, Hou-Ting, Li, Yi-Fan, Liu, Chuan
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5943323/
https://www.ncbi.nlm.nih.gov/pubmed/29576621
http://dx.doi.org/10.1038/s41416-018-0043-8