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Released Mitochondrial DNA Following Intestinal Ischemia Reperfusion Induces the Inflammatory Response and Gut Barrier Dysfunction

Ischemia-reperfusion (I/R) injury is a challenging clinical problem, especially injuries involving the gastrointestinal tract. Mitochondrial DNA (mtDNA) is released upon cell death and stress, and can induce the inflammatory response. We aimed to investigate the role of mtDNA in the pathogenesis of...

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Detalles Bibliográficos
Autores principales: Hu, Qiongyuan, Ren, Huajian, Ren, Jianan, Liu, Qinjie, Wu, Jie, Wu, Xiuwen, Li, Guanwei, Wang, Gefei, Gu, Guosheng, Guo, Kun, Hong, Zhiwu, Liu, Song, Li, Jieshou
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5943336/
https://www.ncbi.nlm.nih.gov/pubmed/29743484
http://dx.doi.org/10.1038/s41598-018-25387-8