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Nuclear p53-mediated repression of autophagy involves PINK1 transcriptional down-regulation
p53 is a transcription factor that is implicated in the control of both apoptotic and autophagic cell death. This tumor suppressor elicits both pro-autophagic and anti-autophagic phenotypes depending of its intracellular localization. The ability of p53 to repress autophagy has been exclusively asso...
Autores principales: | , , , , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Nature Publishing Group UK
2018
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5943347/ https://www.ncbi.nlm.nih.gov/pubmed/29352272 http://dx.doi.org/10.1038/s41418-017-0016-0 |