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Transcriptomic integration of D(4)R and MOR signaling in the rat caudate putamen

Morphine binding to opioid receptors, mainly to μ opioid receptor (MOR), induces alterations in intracellular pathways essential to the initial development of addiction. The activation of the dopamine D(4) receptor (D(4)R), which is expressed in the caudate putamen (CPu), mainly counteracts morphine...

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Detalles Bibliográficos
Autores principales: Valderrama-Carvajal, Alejandra, Irizar, Haritz, Gago, Belén, Jiménez-Urbieta, Haritz, Fuxe, Kjell, Rodríguez-Oroz, María C., Otaegui, David, Rivera, Alicia
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5943359/
https://www.ncbi.nlm.nih.gov/pubmed/29743514
http://dx.doi.org/10.1038/s41598-018-25604-4