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Transcriptomic integration of D(4)R and MOR signaling in the rat caudate putamen
Morphine binding to opioid receptors, mainly to μ opioid receptor (MOR), induces alterations in intracellular pathways essential to the initial development of addiction. The activation of the dopamine D(4) receptor (D(4)R), which is expressed in the caudate putamen (CPu), mainly counteracts morphine...
Autores principales: | , , , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Nature Publishing Group UK
2018
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5943359/ https://www.ncbi.nlm.nih.gov/pubmed/29743514 http://dx.doi.org/10.1038/s41598-018-25604-4 |