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Analysis of early changes in DNA methylation in synovial fibroblasts of RA patients before diagnosis
DNA methylation is an important epigenetic modification that is known to be altered in rheumatoid arthritis synovial fibroblasts (RASF). Here, we compared the status of promoter DNA methylation of SF from patients with very early RA with SF from patients with resolving arthritis, fully established R...
Autores principales: | , , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Nature Publishing Group UK
2018
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5943364/ https://www.ncbi.nlm.nih.gov/pubmed/29743579 http://dx.doi.org/10.1038/s41598-018-24240-2 |