Analysis of early changes in DNA methylation in synovial fibroblasts of RA patients before diagnosis

DNA methylation is an important epigenetic modification that is known to be altered in rheumatoid arthritis synovial fibroblasts (RASF). Here, we compared the status of promoter DNA methylation of SF from patients with very early RA with SF from patients with resolving arthritis, fully established R...

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Detalles Bibliográficos
Autores principales: Karouzakis, Emmanuel, Raza, Karim, Kolling, Christoph, Buckley, Christopher D., Gay, Steffen, Filer, Andrew, Ospelt, Caroline
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2018
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5943364/
https://www.ncbi.nlm.nih.gov/pubmed/29743579
http://dx.doi.org/10.1038/s41598-018-24240-2

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