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TLR3 Mediates Repair and Regeneration of Damaged Neonatal Heart through Glycolysis Dependent YAP1 Regulated miR-152 Expression

The present study investigated whether TLR3 is required for neonatal heart repair and regeneration following myocardial infarction (MI). TLR3 deficient neonatal mice exhibited impaired cardiac functional recovery and a larger infarct size, while wild type neonatal mice showed cardiac functional reco...

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Detalles Bibliográficos
Autores principales: Wang, Xiaohui, Ha, Tuanzhu, Liu, Li, Hu, Yuanping, Kao, Race, Kalbfleisch, John, Williams, David, Li, Chuanfu
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5943401/
https://www.ncbi.nlm.nih.gov/pubmed/29358670
http://dx.doi.org/10.1038/s41418-017-0036-9