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Small GTPases and BAR domain proteins regulate branched actin polymerisation for clathrin and dynamin-independent endocytosis

Using real-time TIRF microscopy imaging, we identify sites of clathrin and dynamin-independent CLIC/GEEC (CG) endocytic vesicle formation. This allows spatio-temporal localisation of known molecules affecting CG endocytosis; GBF1 (a GEF for ARF1), ARF1 and CDC42 which appear sequentially over 60 s,...

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Detalles Bibliográficos
Autores principales: Sathe, Mugdha, Muthukrishnan, Gayatri, Rae, James, Disanza, Andrea, Thattai, Mukund, Scita, Giorgio, Parton, Robert G., Mayor, Satyajit
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5943408/
https://www.ncbi.nlm.nih.gov/pubmed/29743604
http://dx.doi.org/10.1038/s41467-018-03955-w