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NOTCH1 mutation and its prognostic significance in Chinese chronic lymphocytic leukemia: a retrospective study of 317 cases

The proto‐oncogene NOTCH1 is frequently mutated in around 10% of patients with chronic lymphocytic leukemia (CLL). This study analyzed NOTCH1 mutation status of 317 Chinese patients with CLL by Sanger sequencing. The frequencies of NOTCH1 mutation in the PEST (proline (P), glutamic acid (E), serine...

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Detalles Bibliográficos
Autores principales: Zou, Yixin, Fan, Lei, Xia, Yi, Miao, Yi, Wu, Wei, Cao, Lei, Wu, Jiazhu, Zhu, Huayuan, Qiao, Chun, Wang, Li, Xu, Wei, Li, Jianyong
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5943423/
https://www.ncbi.nlm.nih.gov/pubmed/29573199
http://dx.doi.org/10.1002/cam4.1396