Prospective assessment of the predictive value of the BRCA1 gene status in sarcoma patients treated with trabectedin: an updated analysis of the EORTC 62091 trial

We describe the predictive value of BRCA1 gene status on trabectedin efficacy and found no correlation despite the mechanisms of action of this drug that rely on DNA repair systems. [Image: see text]

Detalles Bibliográficos
Autores principales: Italiano, Antoine, Touati, Nathan, Litière, Saskia, Collin, Françoise, Pourquier, Philippe, Gronchi, Alessandro
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2018
Materias:
Clinical Cancer Research
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5943428/
https://www.ncbi.nlm.nih.gov/pubmed/29656586
http://dx.doi.org/10.1002/cam4.1403

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5943428/
https://www.ncbi.nlm.nih.gov/pubmed/29656586
http://dx.doi.org/10.1002/cam4.1403

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