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Anti‐tumor effects of a nonsteroidal anti‐inflammatory drug zaltoprofen on chondrosarcoma via activating peroxisome proliferator‐activated receptor gamma and suppressing matrix metalloproteinase‐2 expression

Surgical resection is the only treatment for chondrosarcomas, because of their resistance to chemotherapy and radiotherapy; therefore, additional strategies are crucial to treat chondrosarcomas. Peroxisome proliferator‐activated receptor gamma (PPAR γ) is a ligand‐activated transcription factor, whi...

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Detalles Bibliográficos
Autores principales: Higuchi, Takashi, Takeuchi, Akihiko, Munesue, Seiichi, Yamamoto, Norio, Hayashi, Katsuhiro, Kimura, Hiroaki, Miwa, Shinji, Inatani, Hiroyuki, Shimozaki, Shingo, Kato, Takashi, Aoki, Yu, Abe, Kensaku, Taniguchi, Yuta, Aiba, Hisaki, Murakami, Hideki, Harashima, Ai, Yamamoto, Yasuhiko, Tsuchiya, Hiroyuki
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5943440/
https://www.ncbi.nlm.nih.gov/pubmed/29573200
http://dx.doi.org/10.1002/cam4.1438