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Anti‐tumor effects of a nonsteroidal anti‐inflammatory drug zaltoprofen on chondrosarcoma via activating peroxisome proliferator‐activated receptor gamma and suppressing matrix metalloproteinase‐2 expression
Surgical resection is the only treatment for chondrosarcomas, because of their resistance to chemotherapy and radiotherapy; therefore, additional strategies are crucial to treat chondrosarcomas. Peroxisome proliferator‐activated receptor gamma (PPAR γ) is a ligand‐activated transcription factor, whi...
Autores principales: | Higuchi, Takashi, Takeuchi, Akihiko, Munesue, Seiichi, Yamamoto, Norio, Hayashi, Katsuhiro, Kimura, Hiroaki, Miwa, Shinji, Inatani, Hiroyuki, Shimozaki, Shingo, Kato, Takashi, Aoki, Yu, Abe, Kensaku, Taniguchi, Yuta, Aiba, Hisaki, Murakami, Hideki, Harashima, Ai, Yamamoto, Yasuhiko, Tsuchiya, Hiroyuki |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
John Wiley and Sons Inc.
2018
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5943440/ https://www.ncbi.nlm.nih.gov/pubmed/29573200 http://dx.doi.org/10.1002/cam4.1438 |
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