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Replication study of polymorphisms associated with response to methotrexate in patients with rheumatoid arthritis

About 70 genetic studies have already addressed the need of biomarkers to predict the response of patients with rheumatoid arthritis (RA) to methotrexate (MTX) treatment. However, no genetic biomarker has yet been sufficiently validated. Here, we aimed to replicate a selection of 25 SNPs in the larg...

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Detalles Bibliográficos
Autores principales: López-Rodríguez, Rosario, Ferreiro-Iglesias, Aida, Lima, Aurea, Bernardes, Miguel, Pawlik, Andrzej, Paradowska-Gorycka, Agnieszka, Świerkot, Jerzy, Slezak, Ryszard, Dolžan, Vita, González-Álvaro, Isidoro, Narváez, Javier, Cáliz, Rafael, Pérez-Pampín, Eva, Mera-Varela, Antonio, Vidal-Bralo, Laura, Acuña Ochoa, José Gorgonio, Conde, Carmen, Gómez-Reino, Juan J., González, Antonio
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5943457/
https://www.ncbi.nlm.nih.gov/pubmed/29743634
http://dx.doi.org/10.1038/s41598-018-25634-y