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Importance of Functional Loss of FUS in FTLD/ALS

Fused in sarcoma (FUS) is an RNA binding protein that regulates RNA metabolism including alternative splicing, transcription, and RNA transportation. FUS is genetically and pathologically involved in frontotemporal lobar degeneration (FTLD)/amyotrophic lateral sclerosis (ALS). Multiple lines of evid...

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Detalles Bibliográficos
Autores principales: Ishigaki, Shinsuke, Sobue, Gen
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5943504/
https://www.ncbi.nlm.nih.gov/pubmed/29774215
http://dx.doi.org/10.3389/fmolb.2018.00044