Clinical Remission of Sight-Threatening Non-Infectious Uveitis Is Characterized by an Upregulation of Peripheral T-Regulatory Cell Polarized Towards T-bet and TIGIT

BACKGROUND: Non-infectious uveitis can cause chronic relapsing and remitting ocular inflammation, which may require high dose systemic immunosuppression to prevent severe sight loss. It has been classically described as an autoimmune disease, mediated by pro-inflammatory Th1 and Th17 T-cell subsets....

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Detalles Bibliográficos
Autores principales: Gilbert, Rose M., Zhang, Xiaozhe, Sampson, Robert D., Ehrenstein, Michael R., Nguyen, Dao X., Chaudhry, Mahid, Mein, Charles, Mahmud, Nadiya, Galatowicz, Grazyna, Tomkins-Netzer, Oren, Calder, Virginia L., Lightman, Sue
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2018
Materias:
Immunology
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5943505/
https://www.ncbi.nlm.nih.gov/pubmed/29774027
http://dx.doi.org/10.3389/fimmu.2018.00907

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5943505/
https://www.ncbi.nlm.nih.gov/pubmed/29774027
http://dx.doi.org/10.3389/fimmu.2018.00907

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