Cargando…
Clinical Remission of Sight-Threatening Non-Infectious Uveitis Is Characterized by an Upregulation of Peripheral T-Regulatory Cell Polarized Towards T-bet and TIGIT
BACKGROUND: Non-infectious uveitis can cause chronic relapsing and remitting ocular inflammation, which may require high dose systemic immunosuppression to prevent severe sight loss. It has been classically described as an autoimmune disease, mediated by pro-inflammatory Th1 and Th17 T-cell subsets....
Autores principales: | Gilbert, Rose M., Zhang, Xiaozhe, Sampson, Robert D., Ehrenstein, Michael R., Nguyen, Dao X., Chaudhry, Mahid, Mein, Charles, Mahmud, Nadiya, Galatowicz, Grazyna, Tomkins-Netzer, Oren, Calder, Virginia L., Lightman, Sue |
---|---|
Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Frontiers Media S.A.
2018
|
Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5943505/ https://www.ncbi.nlm.nih.gov/pubmed/29774027 http://dx.doi.org/10.3389/fimmu.2018.00907 |
Ejemplares similares
-
Small-molecule antagonist of VLA-4 (GW559090) attenuated neuro-inflammation by targeting Th17 cell trafficking across the blood-retinal barrier in experimental autoimmune uveitis
por: Chen, Yi Hsing, et al.
Publicado: (2021) -
Examining the Choroid in Ocular Inflammation: A Focus on Enhanced Depth Imaging
por: Baltmr, Abeir, et al.
Publicado: (2014) -
Vogt–Koyanagi–Harada syndrome – current perspectives
por: Baltmr, Abeir, et al.
Publicado: (2016) -
Ischemic Retinal Vasculitis and Its Management
por: Talat, Lazha, et al.
Publicado: (2014) -
Low-dose cyclosporine treatment for sight-threatening uveitis: Efficacy, toxicity, and tolerance
por: Mathews, D, et al.
Publicado: (2010)