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Genipin alleviates vascular hyperpermeability following hemorrhagic shock by up-regulation of SIRT3/autophagy

Genipin (GP) is commonly used to treat cardiovascular diseases; however, the protective action of GP against vascular hyperpermeability (VH) has not been reported. We previously reported that intrinsic apoptotic signaling (IAS) is involved in VH following hemorrhagic shock (HS). GP inhibits apoptosi...

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Detalles Bibliográficos
Autores principales: Shumin, Cai, Wei, Xu, Yunfeng, Li, Jiangshui, Liang, Youguang, Gao, Zhongqing, Chen, Tao, Li
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5943516/
https://www.ncbi.nlm.nih.gov/pubmed/29760950
http://dx.doi.org/10.1038/s41420-018-0057-2