Screen and Verification for Transgene Integration Sites in Pigs

Efficient transgene expression in recipient cells constitutes the primary step in gene therapy. However, random integration in host genome comprises too many uncertainties. Our study presents a strategy combining bioinformatics and functional verification to find transgene integration sites in pig g...

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Detalles Bibliográficos
Autores principales: Ma, Linyuan, Wang, Yuzhe, Wang, Haitao, Hu, Yiqing, Chen, Jingyao, Tan, Tan, Hu, Man, Liu, Xiaojuan, Zhang, Ran, Xing, Yiming, Zhao, Yiqiang, Hu, Xiaoxiang, Li, Ning
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2018
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5943519/
https://www.ncbi.nlm.nih.gov/pubmed/29743638
http://dx.doi.org/10.1038/s41598-018-24481-1

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5943519/
https://www.ncbi.nlm.nih.gov/pubmed/29743638
http://dx.doi.org/10.1038/s41598-018-24481-1

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