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WSB-1 regulates the metastatic potential of hormone receptor negative breast cancer

BACKGROUND: Metastatic spread is responsible for the majority of cancer-associated deaths. The tumour microenvironment, including hypoxia, is a major driver of metastasis. The aim of this study was to investigate the role of the E3 ligase WSB-1 in breast cancer biology in the context of the hypoxic...

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Detalles Bibliográficos
Autores principales: Poujade, Flore-Anne, Mannion, Aarren, Brittain, Nicholas, Theodosi, Andrew, Beeby, Ellie, Leszczynska, Katarzyna B., Hammond, Ester M., Greenman, John, Cawthorne, Christopher, Pires, Isabel M.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5943535/
https://www.ncbi.nlm.nih.gov/pubmed/29540773
http://dx.doi.org/10.1038/s41416-018-0056-3