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The amino acid selected for generating mutant TbpB antigens defective in binding transferrin can compromise the in vivo protective capacity
Haemophilus parasuis is the causative agent of the Glässer’s disease (GD), one of the most important bacterial diseases that affect young pigs worldwide. GD prevention based on vaccination is a major concern due to the limited cross-protection conferred by the inactivated whole cell vaccines used cu...
Autores principales: | , , , , , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Nature Publishing Group UK
2018
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5943581/ https://www.ncbi.nlm.nih.gov/pubmed/29743502 http://dx.doi.org/10.1038/s41598-018-25685-1 |