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The amino acid selected for generating mutant TbpB antigens defective in binding transferrin can compromise the in vivo protective capacity

Haemophilus parasuis is the causative agent of the Glässer’s disease (GD), one of the most important bacterial diseases that affect young pigs worldwide. GD prevention based on vaccination is a major concern due to the limited cross-protection conferred by the inactivated whole cell vaccines used cu...

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Detalles Bibliográficos
Autores principales: Guizzo, João Antônio, Chaudhuri, Somshukla, Prigol, Simone Ramos, Yu, Rong-hua, Dazzi, Cláudia Cerutti, Balbinott, Natalia, Frandoloso, Gabriela Paraboni, Kreutz, Luiz Carlos, Frandoloso, Rafael, Schryvers, Anthony Bernard
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5943581/
https://www.ncbi.nlm.nih.gov/pubmed/29743502
http://dx.doi.org/10.1038/s41598-018-25685-1