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In breast cancer subtypes steroid sulfatase (STS) is associated with less aggressive tumour characteristics

BACKGROUND: The majority of breast cancer cases are steroid dependent neoplasms, with hormonal manipulation of either CYP19/aromatase or oestrogen receptor alpha axis being the most common therapy. Alternate pathways of steroid actions are documented, but their interconnections and correlations to B...

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Detalles Bibliográficos
Autores principales: McNamara, Keely M, Guestini, Fouzia, Sauer, Torill, Touma, Joel, Bukholm, Ida Rashida, Lindstrøm, Jonas C, Sasano, Hironobu, Geisler, Jürgen
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5943586/
https://www.ncbi.nlm.nih.gov/pubmed/29563635
http://dx.doi.org/10.1038/s41416-018-0034-9