Human Cortex Spheroid with a Functional Blood Brain Barrier for High-Throughput Neurotoxicity Screening and Disease Modeling

The integral selectivity characteristic of the blood brain barrier (BBB) limits therapeutic options for many neurologic diseases and disorders. Currently, very little is known about the mechanisms that govern the dynamic nature of the BBB. Recent reports have focused on the development and applicati...

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Detalles Bibliográficos
Autores principales: Nzou, Goodwell, Wicks, R. T., Wicks, E. E., Seale, S. A., Sane, C. H., Chen, A., Murphy, S. V., Jackson, J. D., Atala, A. J.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2018
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5943588/
https://www.ncbi.nlm.nih.gov/pubmed/29743549
http://dx.doi.org/10.1038/s41598-018-25603-5

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5943588/
https://www.ncbi.nlm.nih.gov/pubmed/29743549
http://dx.doi.org/10.1038/s41598-018-25603-5

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